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ILLINOIS NURSES ASSOCIATION
POSITION PAPER ON PROVIDING PATIENTS SAFE ACCESS TO THERAPEUTIC MARIJUANA/CANNABIS
December 2004

Executive Summary

This position paper addresses the need to support patients who require safe access to therapeutic cannabis. Cannabis has been used throughout the world for medicinal purposes for centuries and has been used safely under appropriate prescriber supervision to treat a great variety of conditions and symptoms. Cannabis is considered by the scientists directly involved with cannabinoid research to be one of the least toxic substances known that delivers a therapeutic response. There are two dimensions in which controversy about the therapeutic use of cannabis is positioned: the scientific and the cultural. In the scientific dimension, there is almost a half-century of research that supports the safety and efficacy of cannabis for conditions such as reducing nausea and vomiting, stimulating appetite, controlling spasticity, decreasing the suffering from the experience of chronic pain, and controlling seizures. In the cultural dimension, there is an embedded mythology about the nature of cannabis sustained in large part to its being designated in the early 20th century as a dangerous narcotic and illegal substance. Cannabis came to be associated with a counter culture underclass such as black jazz musicians, Mexican illegal immigrants, beatniks in the 1950s and hippies in the 1960’s and only recognized for its recreational and illegal use (Dr. Andrew Weil, CNN interview, November 29, 2004).

Illinois nurses have an obligation to the public regarding matters of science and health as well as an obligation to protect the integrity of the profession. A basic principle of the ANA maintains that nurses participate in the profession's efforts to protect the public from misinformation and misrepresentation. Therefore, the Illinois Nurses Association joins the Institute of Medicine (1999), the American Nurses Association (2003) and twelve Constituent Member Associations, the American Public Health Association, and the American Academy of Family Physicians, among other organizations in recognizing the value of science over cultural misrepresentation and supports patients requiring safe access to therapeutic cannabis. The Illinois Nurses Association supports a multi-pronged approach to supporting patients needing cannabis through continued and increased research, education of nurses and the public, advocating for legislation protective of professional prescribers and bona fide patients, and advocating for a federal and state re-scheduling of this currently Schedule I substance.

Background

Historical

Cannabis was an essential part of the American pharmacopoeia until the 1940s and is once again emerging as a significant treatment for persons with serious illness (Zimmer & Morgan, 1997). Cannabis was one of the two most widely used medicinals in the United States until the Marijuana Tax Stamp Act of 1937 began the prohibition of its use under the guise of concern for lost federal tax revenue. Cannabis was designated a Schedule I drug by the Controlled Substances Act of 1970 effectively banning all legal therapeutic use.

Mythologies about cannabis, as with those about gender and race, have been dispelled over the past several decades. In the interest of scientific accuracy and ethical decision-making, nurses have an obligation to educate themselves regarding the embedded inaccuracies and untruths in society about cannabis. Even as the federal government continued to criminalize cannabis use and prosecute individuals, government sponsored commissions and review boards consistently reported findings that supported the safety and decriminalization of cannabis (Zimmer & Morgan, 1997). Zimmer and Morgan cite the New York LaGuardia Commission Report of 1944 as stating “there is no direct relationship between the commission of crimes of violence and marijuana…and marijuana itself has no specific stimulant effect in regard to sexual desires. The use of marijuana does not lead to morphine or cocaine or heroin addiction” (p. xvi). Further, in 1972, President Nixon’s National Commission on Marijuana and Drug Abuse contended that “the Commission is of the unanimous opinion that marijuana use is not such a grave problem that individuals who smoke marijuana, or possess it for that purpose, should be subject to criminal procedures” (p. 2). [It must be noted that since the time of the Commission it has been found that smoking of any substance is hazardous and many other additional routes are currently available to administer therapeutic cannabis].

Nurses, in the interest of public health, will need to examine the mythologies about cannabis they have been accustomed to, such as: cannabis has been scientifically proven harmful, has no medicinal value, is highly addictive, is a gateway drug, kills brain cells, causes crime, damages the fetus, and impairs memory, cognition, and motivation (Zimmer & Morgan). These claims have not been substantiated and in many cases found unsupported by scientific evidence. Indeed, much of the common thinking regarding cannabis can be traced to a foundation of economic self-interest of some professional, business, and institutional groups.

Current State of the Science

The past two decades have provided the opportunity to explore and analyze, from an interdisciplinary perspective, the controversies and conditions in historical and state-of-the-art cannabis science (Joy, Watson, & Benson, (Eds). Institute of Medicine, 1999). The science of cannabis has been examined relevant to ethical, legal, public policy and health policy perspectives. Biochemical fundamentals have been examined and hundreds of relevant clinical trials have been conducted (Grinspoon & Bakalar, 1993). In 2001,the University of California established the Center for Medicinal Cannabis Studies and has at least 14 studies in progress and several pending state and federal approval. This is one of many academic institutions in the United States addressing the need for cannabinoid research. In the United Kingdom, GW Pharmaceuticals has been conducting and completing Phase I and Phase II clinical trials with cannabis-based medicines. GW is currently conducting several Phase III clinical trials involving more than 1,000 participants. One area the British researchers have been studying is the sublingual administration of the THC component of cannabis for patients with intractable pain and a significant analgesic effect has been found (Americans for Safe Access, 2004). Cannabis has been found to have a wide margin for safety with appropriate professional supervision and there is no mortality rate associated with its use.

The growing body of scientific evidence supporting cannabis use has been well documented by the Institute of Medicine (Joy, Watson, & Benson, (Eds.), IOM, 1999) and The American Public Health Association (1995). APHA noted that the therapeutic effects of cannabis appear to work differently from traditional therapeutic and medicinal approaches providing alternative therapy and assistance to patients resistant to conventional modalities. The most common circumstances that cannabis is considered effective for have been in: reducing nausea and vomiting associated with chemotherapy, stimulating appetite for patients with wasting syndromes due to HIV/AIDS and cancer, controlling spasticity associated with spinal cord injury, multiple sclerosis and possibly Parkinson’s disease, decreasing the suffering from the experience of chronic pain, and controlling seizures in a variety of conditions. Less effective is its use for relieving intraocular pressure associated with glaucoma. Current research has indicated favorable preliminary findings of efficacy for conditions such as migraine, arthritis, the agitation associated with Alzheimer’s disease, and attention deficit and hyperactivity disorders among others (The Third National Clinical Conference on Cannabis Therapeutics, 2004).

In spite of the support from major scientific and professional associations such as the American Academy of Family Physicians and the American Nurses Association in addition to IOM and APHA, there are still conflicting opinions and controversy remains among some. The IOM has recommended continued research in cannabinoid science. This research is especially important to determine the number, nature, and efficacy of the many compounds found in the cannabis plant in addition to and aside from the most commonly known compound THC, which is primarily responsible for the psychoactive effects of cannabis but as researchers are finding, not for the analgesic, anti-inflammatory, and anti-emetic properties that are most desired in therapeutic use. Scientists have found that other cannabinoid components such as CBC and particularly CBD have low psychoactive effects but greater anti-inflammatory, analgesic, and anti-emetic efficacy.

Opponents of legitimizing cannabis as a therapeutic often cite the drug dronabinol (Marinol), oral THC, as an approved means of access to the benefits of cannabis. However, perhaps due to the slower absorption rate of orally administered Marinol and the fact that it contains only one cannabinoid compound, THC, “a series of U.S. state studies in the 1980s [found that] cancer patients given a choice between using inhaled marijuana and oral THC overwhelmingly chose cannabis” (Americans for Safe Access, 2004 citing reports to state governments of California, New Mexico, and Tennessee). In addition, oral preparations are an obstacle to relief for many patients. The majority of scientists and patients at The Third National Clinical Conference on Cannabis Therapeutics in Charlottesville, VA in May 2004 concurred that the synthetic form of THC does not deliver as good a therapeutic effect as does natural cannabis which contains in herb form over 60 different cannabinoids, each affecting a different part of the brain at a variety of cannabinoid receptors. It was the conclusion of many of the researchers at the conference that it is a balance of cannabinoid components that is most helpful and efficacious for patients.

Legal Actions and Implications

Nine states (California, Washington, Oregon, Alaska, Hawaii, Arizona, Colorado, Nevada, and Maine) and the District of Columbia have passed therapeutic cannabis laws (ANA, 2003). Voters have approved the use of cannabis, however in several states there have been incidences where administrative and legislative bodies have refused to accept the new regulations or codify provider legislation and where the federal government has arrested legal users. Individuals, families, and providers have risked breaking the law to alleviate suffering and to enhance quality of life for many. Those in the above states who had been at significant risk for criminal consequences from the Drug Enforcement Agency (DEA) will be further protected with the recent Supreme Court decision to uphold the Ninth Circuit Court of Appeals’ ruling that protects individuals and providers in those states from federal prosecution. The 2004 Supreme Court decision to uphold the Ninth Circuit Court of Appeals decision in Conant v. Walters protecting physicians who recommend cannabis to their patients from criminal charges in addition to other judicial decisions such as that of Raich v. Ashcroft has set the precedent for changing cannabis regulation in the nation. In Raich v. Ashcroft a federal appeals court established that it is legal under federal law for patients to grow, possess, and consume cannabis for therapeutic purposes (Americans for Safe Access, 2003). The United States Supreme Court heard arguments in late November 2004 in the case of Ashcroft v. Raich to determine if federal law banning marijuana possession can be enforced in states that have legalized therapeutic cannabis use.

Nursing Actions and Challenges

It is important to note that the impetus to promote the scientific and scholarly agenda on cannabis has been led by two American nurses, Mary Lynn Mathre, MSN, RN, CARN (Virginia Nurses Association) and Melanie Dreher, PhD, RN, FAAN (Iowa Nurses Association) and has facilitated the international dialogue currently taking place among scientists, providers, patients, and legal experts. They recently convened The Third National Clinical Conference on Cannabis Therapeutics in Charlottesville, VA in May 2004 in which over 250 nurses, physicians, patients, and attorneys participated. In 2003, the American Nurses Association passed an action report with recommendations regarding therapeutic cannabis that emphasized advocating for safe patient access to cannabis (ANA, 2003). In addition, twelve of ANA’s CMAs have positions that address the therapeutic use of cannabis: Alaska, Colorado, Connecticut, Hawaii, Minnesota, Mississippi, New Mexico, New York, New Jersey, North Carolina, Virginia, and Wisconsin. The ANA has been progressive and consistent in its approach to this issue going back to the 1996 Congress on Nursing Practice which advocated support for “the education of registered professional nurses regarding current, evidence based therapeutic uses of marijuana/cannabis, and the investigation in controlled trials of the therapeutic efficacy of marijuana/cannabis” (p.5, 2003).

The therapeutic cannabis issue presents many challenges to Illinois nurses including overcoming cultural misconceptions about the substance, understanding the historical standpoints of a variety of public, private, and professional stakeholders, educating themselves on cannabinoid science and its interface with the neurochemistry of the cannabinoid receptor system, listening to and acknowledging the stories of patients, keeping abreast of the components of cannabis-based medicines, their modes of delivery, and efficacy rates, and educating the public. Moreover, nurses need to be aware that as states make provisions for prescriptive marijuana use, the new laws are tending to identify only physician prescriptive authority. Nurses need to act immediately to ensure quality health care access to the public concerning the use of cannabis. This access is clearly incomplete and jeopardized if advanced practice nurses are not included as providers. In addition, there is the obvious economic impact on many nurses if their prescriptive authority regarding cannabis is impeded. At the present, there is a concerted effort to reschedule cannabis from Schedule I to Schedule II or, as many clinicians and scientists suggest, schedule III. It will be up to the nursing associations to protect the interests of nurses’ prescriptive authority and thus, the public’s welfare.

The ANA (2003) action report concluded, “ there is significant research that demonstrates a connection between therapeutic use of marijuana/cannabis and symptom relief. The American Nurses Association needs to actively support patients’ right to legally and safely access marijuana/cannabis for symptom management and to promote quality of life for patients needing such an alternative to conventional therapy” (P.5). The Illinois Nurses Association supports the position of the ANA and will be counted among the organizations that support the right of patients to access legally and safely therapeutic cannabis, and the right of providers to prescribe, without recrimination, therapeutic cannabis for their patients.

POSITION STATEMENT

It is the position of the Illinois Nurses Association to:

1. Support continued research in controlled investigational trials on the therapeutic efficacy of cannabis, including methods of administration.
2. Support the right of patients to have safe access to therapeutic cannabis under appropriate prescriber supervision.
3. Support and encourage the education of registered nurses regarding current, evidence based use of therapeutic cannabis.
4. Support the ability of health care providers to discuss and/or recommend the therapeutic use of cannabis without the threat of intimidation or penalization.
5. Support legislation to remove criminal penalties including arrest and imprisonment for bona fide patients and prescribers of therapeutic cannabis.
6. Support federal and state legislation to include cannabis classification as a Schedule III drug.
(Adapted from ANA, 2003)

REFERENCES

American Public Health Association. (1995). Access to therapeutic marijuana/cannabis. Washington DC.

Americans for Safe Access. (2004). Medical marijuana and cancer, Medical marijuana and chronic pain, Medical marijuana and HIV/AIDS, Medical marijuana and multiple sclerosis. Berkeley, CA. (pamphlets).

American Nurses Association (2003) Providing patients safe access to therapeutic marijuana/cannabis. House of Delegates Action Report with Recommendations.

Grinspoon, L. & Bakalar, JB. (1993). Marijuana, the forbidden medicine. New Haven: Yale University Press.

Joy, JE, Watson, SJ, & Benson, JA. (Ed.s).(1999). Marijuana and medicine: Assessing the science base. Washington, DC.: Institute of Medicine. National Academy Press.

The Third National Clinical Conference on Cannabis Therapeutics. (May 20-22, 2004) University of Virginia, Charlottesville, VA. Conference proceedings.

Zimmer, L. & Morgan, JP. (1997). Marijuana myths, marijuana facts. New York: The Lindesmith Center.

Submitted by the Assembly on Health Policy of the Illinois Nurses Association
November 23, 2004

 
 
 
 
 
 
 
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